• 靶点：
• GK2

• 简介：
• >>Glycerolipid metabolism;>>Metabolic pathways;>>PPAR signaling pathway

• 基因名称：
• GK2

• 蛋白名称：
• Glycerol kinase 2

• Human Gene Id：
• 2712

• Human Swiss Prot No：
• Q14410

• Mouse Swiss Prot No：
• Q9WU65

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human GK2. AA range:281-330

• 特异性：
• GK2 Polyclonal Antibody detects endogenous levels of GK2 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• GK2;GKP2;GKTA;Glycerol kinase 2;GK 2;Glycerokinase 2;ATP:glycerol 3-phosphotransferase 2;Glycerol kinase; testis specific 2

• 实测条带：
• 61kD

• 背景：
• catalytic activity:ATP + glycerol = ADP + sn-glycerol 3-phosphate.,function:Key enzyme in the regulation of glycerol uptake and metabolism.,pathway:Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.,similarity:Belongs to the FGGY kinase family.,subcellular location:In sperm the majority of the enzyme is bound to mitochondria.,

• 功能：
• catalytic activity:ATP + glycerol = ADP + sn-glycerol 3-phosphate.,function:Key enzyme in the regulation of glycerol uptake and metabolism.,pathway:Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.,similarity:Belongs to the FGGY kinase family.,subcellular location:In sperm the majority of the enzyme is bound to mitochondria.,

• 细胞定位：
• Mitochondrion outer membrane ; Single-pass type IV membrane protein . Cytoplasm . In sperm the majority of the enzyme is bound to mitochondria. .

• 组织表达：
• Testis-specific (PubMed:33536340). Expressed in the midpiece of spermatozoa (PubMed:28852571).

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