• 靶点：
• GDF-9

• 简介：
• >>Cytokine-cytokine receptor interaction

• 基因名称：
• GDF9

• 蛋白名称：
• Growth/differentiation factor 9

• Human Gene Id：
• 2661

• Human Swiss Prot No：
• O60383

• Mouse Swiss Prot No：
• Q07105

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human GDF-9. AA range:273-322

• 特异性：
• GDF-9 Polyclonal Antibody detects endogenous levels of GDF-9 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• GDF9;Growth/differentiation factor 9;GDF-9

• 实测条带：
• 57kD

• 背景：
• This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates ovarian function. Reduced expression of this gene may be associated with polycystic ovary syndrome and mutations in this gene may be more common in mothers of dizygotic twins. [provided by RefSeq, Jul 2016],

• 功能：
• function:Required for ovarian folliculogenesis.,similarity:Belongs to the TGF-beta family.,subunit:Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.,

• 细胞定位：
• Secreted .

• 组织表达：
• Expressed in ovarian granulosa cells. Present in oocytes of primary follicles (at protein level).

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