Gasdermin C Polyclonal Antibody
- 货号：YT1855
- 应用：WB IF;ELISA
- 种属：Human;Rat;Mouse;
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human GSDMC. AA range:109-158
- 特异性：
- Gasdermin C Polyclonal Antibody detects endogenous levels of Gasdermin C protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500-2000 IF 1:100-300 ELISA 1:5000-20000 Not yet tested in other applications.
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- GSDMC;MLZE;Gasdermin-C;Melanoma-derived leucine zipper-containing extranuclear factor
- 背景：
- caution:Despite its name, it is unclear if this protein contains a functional leucine zipper.,similarity:Belongs to the gasdermin family.,tissue specificity:Expressed primarily in trachea and spleen.,
- 功能：
- caution:Despite its name, it is unclear if this protein contains a functional leucine zipper.,similarity:Belongs to the gasdermin family.,tissue specificity:Expressed primarily in trachea and spleen.,
- 细胞定位：
- [Gasdermin-C]: Cytoplasm, cytosol .; [Gasdermin-C, N-terminal]: Cell membrane ; Multi-pass membrane protein .
- 组织表达：
- Expressed mainly in trachea and spleen (PubMed:11223543). In the esophagus, expressed in differentiating cells and probably in differentiated cells. Also detected in gastric epithelium (PubMed:19051310).
- Immunofluorescence analysis of A549. 1,primary Antibody was diluted at 1:200(4°C overnight). 2, Goat Anti Rabbit IgG (H&L) - Alexa Fluor 488 Secondary antibody was diluted at 1:1000(room temperature, 50min).3, Picture B: DAPI(blue) 10min.
- Western Blot analysis of various cells using Gasdermin C Polyclonal Antibody diluted at 1:500
- Western blot analysis of GSDMC Antibody. The lane on the right is blocked with the GSDMC peptide.
- Western blot analysis of the lysates from HepG2 cells using GSDMC antibody.
