Galectin-7 Polyclonal Antibody
- 货号：YT1839
- 应用：IHC;IF;WB;ELISA
- 种属：Human;Mouse;Rat
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human LEG7. AA range:41-90
- 特异性：
- Galectin-7 Polyclonal Antibody detects endogenous levels of Galectin-7 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500-2000 IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- LGALS7;PIG1;LGALS7B;Galectin-7;Gal-7;HKL-14;PI7;p53-induced gene 1 protein
- 背景：
- The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridization studies indicate that this lectin is specifically expressed in keratinocytes and found mainly in stratified squamous epithelium. A duplicate copy of this gene (GeneID:653499) is found adjacent to, but on the opposite strand on chromosome 19. [provided by RefSeq, Jul 2008],
- 功能：
- function:Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release.,induction:By p53.,online information:Galectin-7,similarity:Contains 1 galectin domain.,subcellular location:May be secreted by a non-classical secretory pathway.,subunit:Monomer.,tissue specificity:Mainly in stratified squamous epithelium.,
- 细胞定位：
- Cytoplasm . Nucleus . Secreted . May be secreted by a non-classical secretory pathway.
- 组织表达：
- Mainly expressed in stratified squamous epithelium.
- Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
