• 靶点：
• GADD 45γ

• 简介：
• >>MAPK signaling pathway;>>NF-kappa B signaling pathway;>>FoxO signaling pathway;>>Cell cycle;>>p53 signaling pathway;>>Apoptosis;>>Cellular senescence;>>Epstein-Barr virus infection;>>Pathways in cancer;>>Transcriptional misregulation in cancer;>>Colorectal cancer;>>Pancreatic cancer;>>Endometrial cancer;>>Glioma;>>Thyroid cancer;>>Basal cell carcinoma;>>Melanoma;>>Chronic myeloid leukemia;>>Small cell lung cancer;>>Non-small cell lung cancer;>>Breast cancer;>>Hepatocellular carcinoma;>>Gastric cancer

• 基因名称：
• GADD45G

• 蛋白名称：
• Growth arrest and DNA damage-inducible protein GADD45 gamma

• Human Gene Id：
• 10912

• Human Swiss Prot No：
• O95257

• Mouse Swiss Prot No：
• Q9Z111

• Rat Gene Id：
• 291005

• Rat Swiss Prot No：
• Q9WTQ7

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human GA45G. AA range:101-150

• 特异性：
• GADD 45γ Polyclonal Antibody detects endogenous levels of GADD 45γ protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• GADD45G;CR6;DDIT2;Growth arrest and DNA damage-inducible protein GADD45 gamma;Cytokine-responsive protein CR6;DNA damage-inducible transcript 2 protein;DDIT-2

• 实测条带：
• 19kD

• 背景：
• This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta. [provided by RefSeq, Jul 2008],

• 功能：
• function:Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.,similarity:Belongs to the GADD45 family.,subunit:Interacts with GADD45GIP1.,

• 细胞定位：
• nucleus,cytoplasm,

• 组织表达：
• Brain,Colon carcinoma,Lung,Placenta,

Light Emitting Diodes Irradiation Regulates miRNA-877-3p to Promote Cardiomyocyte Proliferation International Journal of Medical Sciences Yu Liu WB Mouse
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