- 靶点:
- FoxJ1
- 基因名称:
- FOXJ1
- 蛋白名称:
- Forkhead box protein J1
- Human Gene Id:
- 2302
- Human Swiss Prot No:
- Q92949
- Mouse Gene Id:
- 15223
- Mouse Swiss Prot No:
- Q61660
- Rat Gene Id:
- 116557
- Rat Swiss Prot No:
- Q63247
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human FOXJ1. AA range:271-320
- 特异性:
- FoxJ1 Polyclonal Antibody detects endogenous levels of FoxJ1 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 浓度:
- 1 mg/ml
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- FOXJ1;FKHL13;HFH4;Forkhead box protein J1;Forkhead-related protein FKHL13;Hepatocyte nuclear factor 3 forkhead homolog 4;HFH-4
- 实测条带:
- 60kD
- 背景:
- This gene encodes a member of the forkhead family of transcription factors. Similar genes in zebrafish and mouse have been shown to regulate the transcription of genes that control the production of motile cilia. The mouse ortholog also functions in the determination of left-right asymmetry. Polymorphisms in this gene are associated with systemic lupus erythematosus and allergic rhinitis.[provided by RefSeq, Sep 2009],
- 功能:
- developmental stage:Expressed in developing lung, kidney and central nervous system.,disease:Genetic variations in FOXJ1 may be associated with susceptibility to allergic rhinitis (ALRH) [MIM:607154]. Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure.,function:May play an important role in cell fate determination during lung development and in spermatogenesis.,similarity:Contains 1 fork-head DNA-binding domain.,tissue specificity:Testis, oviduct, lung and brain cortex.,
- 细胞定位:
- Nucleus .
- 组织表达:
- Testis, oviduct, lung and brain cortex.
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- Antibody-FAQs
- 产品图片
- Western Blot analysis of LOVO cells using FoxJ1 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
- Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
- Western blot analysis of lysates from LOVO cells, using FOXJ1 Antibody. The lane on the right is blocked with the synthesized peptide.