Fibulin-2 Polyclonal Antibody

    • 货号:YT1707
    • 应用:WB;IHC;IF;ELISA
    • 种属:Human;Rat;Mouse;
      • 靶点:
      • Fibulin-2
      • 基因名称:
      • FBLN2
      • 蛋白名称:
      • Fibulin-2
      • Human Gene Id:
      • 2199
      • Human Swiss Prot No:
      • P98095
      • Mouse Swiss Prot No:
      • P37889
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human FBLN2. AA range:241-290
      • 特异性:
      • Fibulin-2 Polyclonal Antibody detects endogenous levels of Fibulin-2 protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • FBLN2;Fibulin-2;FIBL-2
      • 实测条带:
      • 130kD
      • 背景:
      • This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
      • 功能:
      • developmental stage:Widely expressed during embryonic development. Primarily detected within the neuropithelium, spinal ganglia and peripheral nerves.,function:Its binding to fibronectin and some other ligands is calcium dependent.,similarity:Belongs to the fibulin family.,similarity:Contains 11 EGF-like domains.,similarity:Contains 3 anaphylatoxin-like domains.,subunit:Homotrimer; disulfide-linked. Interacts with LAMA2.,tissue specificity:Component of both basement membranes and other connective tissues. Expressed in heart, placenta and ovary.,
      • 细胞定位:
      • Secreted, extracellular space, extracellular matrix.
      • 组织表达:
      • Component of both basement membranes and other connective tissues. Expressed in heart, placenta and ovary.

      Proteomic Analysis of the Supernatant from Bone Marrow Mesenchymal Stem Cells under High Glucose Conditions JOURNAL OF PROTEOME RESEARCH Guoqing Li WB Human bone marrow mesenchymal stem cells (BMSCs)
      货号:YT1707

      • 产品图片
      • Western Blot analysis of various cells using Fibulin-2 Polyclonal Antibody diluted at 1:500
      • Immunofluorescence analysis of A549 cells, using FBLN2 Antibody. The picture on the right is blocked with the synthesized peptide.
      • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using FBLN2 Antibody. The picture on the right is blocked with the synthesized peptide.