FGF-13 Polyclonal Antibody
- 货号:YT1696
- 应用:WB;ELISA
- 种属:Human;Mouse;Rat
- 蛋白名称:
- Fibroblast growth factor 13
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human FGF13. AA range:154-203
- 特异性:
- FGF-13 Polyclonal Antibody detects endogenous levels of FGF-13 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- FGF13;FHF2;Fibroblast growth factor 13;FGF-13;Fibroblast growth factor homologous factor 2;FHF-2
- 背景:
- The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked mental retardation mapping to this region. Alternative splicing of this gene at the 5' end results in several transcript variants encoding different isoforms with different N-termini. [provided by RefSeq, Nov 2008],
- 功能:
- function:Probably involved in nervous system development and function.,similarity:Belongs to the heparin-binding growth factors family.,tissue specificity:Nervous system.,
- 细胞定位:
- [Isoform 1]: Nucleus .; [Isoform 2]: Cytoplasm . Nucleus .; [Isoform 3]: Cytoplasm . Nucleus .; [Isoform 4]: Cytoplasm . Nucleus .; [Isoform 5]: Cytoplasm . Nucleus .; Cell projection, filopodium . Cell projection, growth cone . Cell projection, dendrite . Cell membrane, sarcolemma . Cytoplasm . Not secreted. Localizes to the lateral membrane and intercalated disks of myocytes. .
- 组织表达:
- Ubiquitously expressed. Predominantly expressed in the nervous system.
- Western Blot analysis of JK cells using FGF-13 Polyclonal Antibody diluted at 1:500
- Western blot analysis of the lysates from Jurkat cells using FGF13 antibody.