• 靶点：
• Fe65L

• 基因名称：
• APBB2

• 蛋白名称：
• Amyloid beta A4 precursor protein-binding family B member 2

• Human Gene Id：
• 323

• Human Swiss Prot No：
• Q92870

• Mouse Gene Id：
• 11787

• Mouse Swiss Prot No：
• Q9DBR4

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human APBB2. AA range:471-520

• 特异性：
• Fe65L Polyclonal Antibody detects endogenous levels of Fe65L protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• APBB2;FE65L;FE65L1;Amyloid beta A4 precursor protein-binding family B member 2;Protein Fe65-like 1

• 实测条带：
• 83kD

• 背景：
• amyloid beta precursor protein binding family B member 2(APBB2) Homo sapiens The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],

• 功能：
• function:May modulate the internalization of beta-amyloid precursor protein.,similarity:Contains 1 WW domain.,similarity:Contains 2 PID domains.,subunit:Binds to the intracellular domain of the beta-amyloid precursor protein.,

• 细胞定位：
• Endoplasmic reticulum . Golgi apparatus . Early endosome .

• 组织表达：
• Widely expressed.

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