• 靶点：
• FAM111B

• 基因名称：
• FAM111B

• 蛋白名称：
• Protein FAM111B

• Human Gene Id：
• 374393

• Human Swiss Prot No：
• Q6SJ93

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human F111B. AA range:281-330

• 特异性：
• FAM111B Polyclonal Antibody detects endogenous levels of FAM111B protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• IHC 1:100 - 1:200. ELISA: 1:5000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• FAM111B;CANP;Protein FAM111B;Cancer-associated nucleoprotein

• 分子量：
• 85kD

• 背景：
• This gene encodes a protein with a trypsin-like cysteine/serine peptidase domain in the C-terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP). Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog of this gene which also has a trypsin‐like peptidase domain, FAM111A, is located only 16 kb from this gene on human chromosome 11q12.1. [provided by RefSeq, Apr 2014],

• 功能：
• sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the FAM111 family.,

• 组织表达：
• Widely expressed.

DNMT3B-mediated FAM111B methylation promotes papillary thyroid tumor glycolysis, growth and metastasis International Journal of Biological Sciences Yimeng Du WB,IHC Human
货号：YT1669

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