• 靶点：
• CYP2U1

• 简介：
• >>Fatty acid degradation;>>Arachidonic acid metabolism;>>Metabolic pathways

• 基因名称：
• CYP2U1

• 蛋白名称：
• Cytochrome P450 2U1

• Human Gene Id：
• 113612

• Human Swiss Prot No：
• Q7Z449

• Mouse Gene Id：
• 71519

• Mouse Swiss Prot No：
• Q9CX98

• Rat Gene Id：
• 310848

• Rat Swiss Prot No：
• Q4V8D1

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human Cytochrome P450 2U1. AA range:281-330

• 特异性：
• CYP2U1 Polyclonal Antibody detects endogenous levels of CYP2U1 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• CYP2U1;Cytochrome P450 2U1

• 实测条带：
• 61kD

• 背景：
• This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a hydroxylase that metabolizes arachidonic acid, docosahexaenoic acid, and other long chain fatty acids. [provided by RefSeq, Jul 2008],

• 功能：
• catalytic activity:RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O.,cofactor:Heme group.,developmental stage:Expressed in fetal thymus.,function:Catalyzes the hydroxylation of arachidonic acid, docosahexaenoic acid and other long chain fatty acids. May modulate the arachidonic acid signaling pathway and play a role in other fatty acid signaling processes.,similarity:Belongs to the cytochrome P450 family.,tissue specificity:Widely expressed with stronger expression in thymus, heart and cerebellum.,

• 细胞定位：
• Endoplasmic reticulum membrane ; Multi-pass membrane protein . Microsome membrane ; Multi-pass membrane protein . Mitochondrion inner membrane ; Multi-pass membrane protein .

• 组织表达：
• Widely expressed with stronger expression in thymus, heart and cerebellum.

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