• 靶点：
• COX5b

• 简介：
• >>Oxidative phosphorylation;>>Metabolic pathways;>>Cardiac muscle contraction;>>Thermogenesis;>>Non-alcoholic fatty liver disease;>>Alzheimer disease;>>Parkinson disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Chemical carcinogenesis - reactive oxygen species;>>Diabetic cardiomyopathy

• 基因名称：
• COX5B

• 蛋白名称：
• Cytochrome c oxidase subunit 5B mitochondrial

• Human Gene Id：
• 1329

• Human Swiss Prot No：
• P10606

• Mouse Swiss Prot No：
• P19536

• Rat Gene Id：
• 94194

• Rat Swiss Prot No：
• P12075

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human COX5B. AA range:11-60

• 特异性：
• COX5b Polyclonal Antibody detects endogenous levels of COX5b protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• COX5B;Cytochrome c oxidase subunit 5B; mitochondrial;Cytochrome c oxidase polypeptide Vb

• 分子量：
• 14kD

• 背景：
• Cytochrome C oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Vb of the human mitochondrial respiratory chain enzyme. [provided by RefSeq, Jul 2008],

• 功能：
• function:This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.,similarity:Belongs to the cytochrome c oxidase subunit 5B family.,

• 细胞定位：
• Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side .

• 组织表达：
• Liver,Skin,

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