COL14A1 Polyclonal Antibody
- 货号：YT1012
- 应用：IHC;IF;ELISA
- 种属：Human;Mouse
- 简介：
- >>Protein digestion and absorption
- 蛋白名称：
- Collagen alpha-1(XIV) chain
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human N-ternal Collagen XIV alpha1. AA range:71-120
- 特异性：
- COL14A1 Polyclonal Antibody detects endogenous levels of COL14A1 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- COL14A1;UND;Collagen alpha-1(XIV) chain;Undulin
- 背景：
- This gene encodes the alpha chain of type XIV collagen, a member of the FACIT (fibril-associated collagens with interrupted triple helices) collagen family. Type XIV collagen interacts with the fibril surface and is involved in the regulation of fibrillogenesis. [provided by RefSeq, Jan 2013],
- 功能：
- function:Plays an adhesive role by integrating collagen bundles. It is probably associated with the surface of interstitial collagen fibrils via COL1. The COL2 domain may then serve as a rigid arm which sticks out from the fibril and protrudes the large N-terminal globular domain into the extracellular space, where it might interact with other matrix molecules or cell surface receptors.,PTM:Lysines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in all cases and bind carbohydrates.,PTM:May contain numerous cysteine residues involved in inter- and intramolecular disulfide bonding.,PTM:Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.,similarity:Belongs to the fibril-associated collagens with interrupted helices (FACIT) family.,similarity:Contains 1 TSP N-terminal (TSPN) domain.,similarity:
- 细胞定位：
- Secreted, extracellular space, extracellular matrix .
- 组织表达：
- Brain,Liver,Muscle,PNS,Testis,
- Immunofluorescence analysis of HeLa cells, using Collagen XIV alpha1 Antibody. The picture on the right is blocked with the synthesized peptide.
- Immunohistochemistry analysis of paraffin-embedded human heart tissue, using Collagen XIV alpha1 Antibody. The picture on the right is blocked with the synthesized peptide.
