• 靶点：
• CNK1

• 基因名称：
• CNKSR1

• 蛋白名称：
• Connector enhancer of kinase suppressor of ras 1

• Human Gene Id：
• 10256

• Human Swiss Prot No：
• Q969H4

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human CNKR1. AA range:491-540

• 特异性：
• CNK1 Polyclonal Antibody detects endogenous levels of CNK1 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• CNKSR1;CNK1;Connector enhancer of kinase suppressor of ras 1;Connector enhancer of KSR 1;CNK homolog protein 1;CNK1;hCNK1;Connector enhancer of KSR-like

• 实测条带：
• 80kD

• 背景：
• This gene encodes a protein containing several motifs involved in protein-protein interaction, including PDZ, PH (Pleckstrin homology), and SAM (sterile alpha motif) domains. The encoded protein acts as a scaffold component for receptor tyrosine kinase signaling and may mediate crosstalk between different signaling pathways. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],

• 功能：
• function:May function as an adapter protein or regulator of Ras signaling pathways.,PTM:Phosphorylated on tyrosine.,similarity:Belongs to the CNKSR family.,similarity:Contains 1 CRIC domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 SAM (sterile alpha motif) domain.,subunit:Interacts with RHO and RALGDS.,

• 细胞定位：
• Cytoplasm . Membrane ; Peripheral membrane protein .

• 组织表达：
• Brain,Epithelium,Kidney,Liver,Neuroepithelium,Place

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