- 靶点:
- CMTM4
- 基因名称:
- CMTM4
- 蛋白名称:
- CKLF-like MARVEL transmembrane domain-containing protein 4
- Human Gene Id:
- 146223
- Human Swiss Prot No:
- Q8IZR5
- Mouse Gene Id:
- 97487
- Mouse Swiss Prot No:
- Q8CJ61
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human CKLF4. AA range:161-210
- 特异性:
- CMTM4 Polyclonal Antibody detects endogenous levels of CMTM4 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 浓度:
- 1 mg/ml
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- CMTM4;CKLFSF4;CKLF-like MARVEL transmembrane domain-containing protein 4;Chemokine-like factor superfamily member 4
- 实测条带:
- 26kD
- 背景:
- This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
- 功能:
- similarity:Belongs to the chemokine-like factor family.,similarity:Contains 1 MARVEL domain.,tissue specificity:Highly expressed in testis and prostate.,
- 细胞定位:
- Membrane ; Multi-pass membrane protein .
- 组织表达:
- Highly expressed in testis and prostate.
CMTM4 regulates epithelial–mesenchymal transition and PD-L1 expression in head and neck squamous cell carcinoma. MOLECULAR CARCINOGENESIS Mol Carcinogen. 2021 Aug;60(8):556-566 IHC Human mucosa,dysplasia tissue,HNSCC tissue
货号:YT0986
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- Antibody-FAQs
- 产品图片
- Immunofluorescence analysis of A549. 1,primary Antibody(red) was diluted at 1:200(4°C overnight). 2, Goat Anti Rabbit IgG (H&L) - Alexa Fluor 594 Secondary antibody was diluted at 1:1000(room temperature, 50min).3, Picture B: DAPI(blue) 10min.
- Western Blot analysis of HELA cells using CMTM4 Polyclonal Antibody
- Western blot analysis of CKLF4 Antibody. The lane on the right is blocked with the CKLF4 peptide.
- Immunohistochemistryt analysis of paraffin-embedded human breast carcinoma, using CKLF4 Antibody. The lane on the right is blocked with the CKLF4 peptide.