CIP29 Polyclonal Antibody

    • 货号:YT0930
    • 应用:WB;IHC;IF;ELISA
    • 种属:Human;Mouse;Rat
      • 靶点:
      • CIP29
      • 基因名称:
      • SARNP
      • 蛋白名称:
      • SAP domain-containing ribonucleoprotein
      • Human Swiss Prot No:
      • P82979
      • Mouse Swiss Prot No:
      • Q9D1J3
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human HCC1. AA range:147-196
      • 特异性:
      • CIP29 Polyclonal Antibody detects endogenous levels of CIP29 protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • SARNP;HCC1;HSPC316;SAP domain-containing ribonucleoprotein;Cytokine-induced protein of 29 kDa;Nuclear protein Hcc-1;Proliferation-associated cytokine-inducible protein CIP29
      • 实测条带:
      • 30kD
      • 背景:
      • This gene encodes a protein that is upregulated in response to various cytokines. The encoded protein may play a role in cell cycle progression. A translocation between this gene and the myeloid/lymphoid leukemia gene, resulting in expression of a chimeric protein, has been associated with acute myelomonocytic leukemia. Pseudogenes exist on chromosomes 7 and 8. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009],
      • 功能:
      • transcription, regulation of transcription, DNA-dependent, regulation of translation, posttranscriptional regulation of gene expression, regulation of cellular protein metabolic process, regulation of transcription, regulation of RNA metabolic process,
      • 细胞定位:
      • Nucleus. Nucleus speckle.
      • 组织表达:
      • Low expression in spleen, liver, pancreas, testis, thymus, heart, and kidney. Increased levels are seen in hepatocellular carcinoma and pancreatic adenocarcinoma.
      • 产品图片
      • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using HCC1 Antibody. The picture on the right is blocked with the synthesized peptide.
      • Western blot analysis of lysates from mouse liver, using HCC1 Antibody. The lane on the right is blocked with the synthesized peptide.