• 靶点：
• Cadherin-20

• 基因名称：
• CDH20

• 蛋白名称：
• Cadherin-20

• Human Gene Id：
• 28316

• Human Swiss Prot No：
• Q9HBT6

• Mouse Gene Id：
• 23836

• Mouse Swiss Prot No：
• Q9Z0M3

• Rat Gene Id：
• 363948

• Rat Swiss Prot No：
• Q5DWV1

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human CDH20. AA range:111-160

• 特异性：
• Cadherin-20 Polyclonal Antibody detects endogenous levels of Cadherin-20 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• CDH20;CDH7L3;Cadherin-20

• 分子量：
• 89kD

• 背景：
• This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes. [provided by RefSeq, Jul 2008],

• 功能：
• function:Cadherins are calcium dependent cell adhesion proteins.,function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.,similarity:Contains 5 cadherin domains.,tissue specificity:Expressed in placenta, adult brain, and fetal brain.,

• 细胞定位：
• Cell membrane; Single-pass type I membrane protein.

• 组织表达：
• Expressed in placenta, adult brain, and fetal brain.

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