BCL2L12 Polyclonal Antibody
- 货号：YT0472
- 应用：WB;ELISA
- 种属：Human;Mouse
- 蛋白名称：
- Bcl-2-like protein 12
- 免疫原：
- Synthesized peptide derived from BCL2L12 . at AA range: 60-140
- 特异性：
- BCL2L12 Polyclonal Antibody detects endogenous levels of BCL2L12 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- BCL2L12;BPR;Bcl-2-like protein 12;Bcl2-L-12;Bcl-2-related proline-rich protein
- 背景：
- This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],
- 功能：
- similarity:Belongs to the Bcl-2 family.,tissue specificity:Expressed mainly in breast, thymus, prostate, fetal liver, colon, placenta, pancreas, small intestine, spinal cord, kidney, and bone marrow and to a lesser extent in many other tissues. Isoform 2 is primarily expressed in skeletal muscle.,
- 组织表达：
- Expressed mainly in breast, thymus, prostate, fetal liver, colon, placenta, pancreas, small intestine, spinal cord, kidney, and bone marrow and to a lesser extent in many other tissues. Isoform 2 is primarily expressed in skeletal muscle.
- Western blot analysis of lysates from Jurkat cells, primary antibody was diluted at 1:1000, 4°over night
