Ameloblastin Polyclonal Antibody
- 货号：YT0209
- 应用：WB;ELISA
- 种属：Human;Rat;Mouse;
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human Ameloblastin. AA range:275-324
- 特异性：
- Ameloblastin Polyclonal Antibody detects endogenous levels of Ameloblastin protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 背景：
- This gene encodes the nonamelogenin enamel matrix protein ameloblastin. The encoded protein may be important in enamel matrix formation and mineralization. This gene is located in the calcium-binding phosphoprotein gene cluster on chromosome 4. Mutations in this gene may be associated with dentinogenesis imperfect and autosomal dominant amylogenesis imperfect. [provided by RefSeq, Aug 2011],
- 功能：
- disease:Defects in AMBN are found in patients with ameloblastomas.,function:Involved in the mineralization and structural organization of enamel.,similarity:Belongs to the ameloblastin family.,tissue specificity:Ameloblast-specific. Located at the Tomes processes of secretory ameloblasts and in the sheath space between rod-interrod enamel.,
- 细胞定位：
- Secreted, extracellular space, extracellular matrix.
- 组织表达：
- Ameloblast-specific. Located at the Tomes processes of secretory ameloblasts and in the sheath space between rod-interrod enamel.
- Western blot analysis of lysates from HeLa cells, using Ameloblastin antibody.
