• 靶点：
• ABHD7

• 简介：
• >>Chemical carcinogenesis - receptor activation;>>Chemical carcinogenesis - reactive oxygen species

• 基因名称：
• EPHX4

• 蛋白名称：
• Epoxide hydrolase 4

• Human Gene Id：
• 253152

• Human Swiss Prot No：
• Q8IUS5

• Mouse Gene Id：
• 384214

• Mouse Swiss Prot No：
• Q6IE26

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human ABHD7. AA range:101-150

• 特异性：
• ABHD7 Polyclonal Antibody detects endogenous levels of ABHD7 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• EPHX4;ABHD7;EPHXRP;Epoxide hydrolase 4;Abhydrolase domain-containing protein 7;Epoxide hydrolase-related protein

• 实测条带：
• 42kD

• 背景：
• The α/β hydrolase superfamily comprise diverse members that are involved in important biochemical processes and related to various diseases. They have unrelated sequences, various substrates, and different kinds of catalytic activities, yet they share the same canonical α/β hydrolase fold, which consists of an eight-stranded parallel α/β structure. They are also characterized by a catalytic triad composed of a histidine, an acid and a nucleophile. Members of this superfamily are often drug targets for treating diseases, such as diabetes, Alzheimer's disease, obesity and blood clotting disorders. The Ab hydrolase domain containing (ABHD) gene subfamily is comprised of 15 mostly uncharacterized members, most of which utilize a serine nucleophile to form the G-X-S-X-G nucleophile elbow. ABHD7 is a 362 amino acid single-pass type II membrane protein that belongs to the AB hydrolase superfamily and the Epoxide hydrolase family.

• 细胞定位：
• Membrane ; Single-pass type II membrane protein .

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