• 靶点：
• QIK/QSK

• 简介：
• >>Glucagon signaling pathway

• 基因名称：
• SIK2 KIAA0781 QIK SNF1LK2

• 蛋白名称：
• QIK/QSK (Phospho-Thr175/163)

• Human Gene Id：
• 23235

• Human Swiss Prot No：
• Q9H0K1

• Mouse Gene Id：
• 235344

• Mouse Swiss Prot No：
• Q8CFH6

• 免疫原：
• Synthesized peptide derived from human QIK/QSK (Phospho-Thr175/163)

• 特异性：
• This antibody detects endogenous levels of QIK/QSK (Phospho-Thr175/163) at Human, Mouse,Rat

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500-2000

• 纯化工艺：
• The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2)

• 实测条带：
• 105kD

• 功能：
• catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-175 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,function:Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 UBA domain.,subunit:Interacts with and phosphorylates TORC2/CRTC2.,

• 细胞定位：
• Cytoplasm . Endoplasmic reticulum membrane .

• 组织表达：
• Brain,Colon,Lung,Testis,

• June 19-2018
• WESTERN IMMUNOBLOTTING PROTOCOL

• June 19-2018
• IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL

• June 19-2018
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• September 08-2020
• FLOW-CYTOMEYRT-PROTOCOL

• May 20-2022
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• July 13-2018
• CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN

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• July 13-2018
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