PPIG (Phospho Ser376) rabbit pAb

    • 货号:YP1448
    • 应用:WB;IHC
    • 种属:Human;Mouse;Rat
      • 靶点:
      • PPIG
      • 基因名称:
      • PPIG
      • 蛋白名称:
      • PPIG (Ser376)
      • Human Gene Id:
      • 9360
      • Human Swiss Prot No:
      • Q13427
      • Mouse Swiss Prot No:
      • A2AR02
      • 免疫原:
      • Synthesized phosho peptide around human PPIG (Ser376)
      • 特异性:
      • This antibody detects endogenous levels of Human Mouse Rat PPIG (phospho-Ser376)
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500-2000;IHC 1:50-300
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • Peptidyl-prolyl cis-trans isomerase G (PPIase G) (Peptidyl-prolyl isomerase G) (EC 5.2.1.8) (CASP10) (Clk-associating RS-cyclophilin) (CARS-Cyp) (CARS-cyclophilin) (SR-cyclophilin) (SR-cyp) (SRcyp) (Cyclophilin G) (Rotamase G)
      • 实测条带:
      • 82kD
      • 功能:
      • catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,domain:The RS domain is required for the interaction with the phosphorylated C-terminal domain of RNA polymerase II.,enzyme regulation:Cyclosporin A (CsA)-sensitive.,function:PPIases accelerate the folding of proteins.,function:PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.,function:PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the cyclophilin-type PPIase family.,similarity:Contains 1 PPIase cyclophilin-type domain.,subcell
      • 细胞定位:
      • Nucleus matrix . Nucleus speckle . Colocalizes with RNA splicing factors at nuclear speckles. .
      • 组织表达:
      • Ubiquitous.
      • 产品图片
      • Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).