• 靶点：
• IPP-2

• 基因名称：
• PPP1R2

• 蛋白名称：
• Protein phosphatase inhibitor 2

• Human Gene Id：
• 5504

• Human Swiss Prot No：
• P41236

• Mouse Gene Id：
• 66849

• Mouse Swiss Prot No：
• Q9DCL8

• Rat Gene Id：
• 192361

• Rat Swiss Prot No：
• P50411

• 免疫原：
• Synthesized phospho-peptide around the phosphorylation site of human IPP-2 (phospho Ser44)

• 特异性：
• Phospho-IPP-2 (S44) Polyclonal Antibody detects endogenous levels of IPP-2 protein only when phosphorylated at S44.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• PPP1R2;IPP2;Protein phosphatase inhibitor 2;IPP-2

• 实测条带：
• 44kD

• 背景：
• Protein phosphatase-1 (PP1) is one of the main eukaryotic serine/threonine phosphatases. The protein encoded by this gene binds to the catalytic subunit of PP1, strongly inhibiting its activity. Ten related pseudogenes have been found throughout the human genome. Several splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015],

• 功能：
• function:Inhibitor of protein-phosphatase 1.,PTM:Phosphorylation on Thr-73 by GSK3 activates PP1 by dissociating the PP1-PPP1R2 complex (By similarity). Phosphorylation on Ser-44 by ATM activates PP1 by dissociating the PP1-PPP1R2 complex.,similarity:Belongs to the protein phosphatase inhibitor 2 family.,subunit:Heterodimer with PP1.,

• 细胞定位：
• protein phosphatase type 1 complex,

• 组织表达：
• Epithelium,Heart,Platelet,Skin,Testis,

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