• 靶点：
• RGS16

• 基因名称：
• RGS16

• 蛋白名称：
• Regulator of G-protein signaling 16

• Human Gene Id：
• 6004

• Human Swiss Prot No：
• O15492

• Mouse Gene Id：
• 19734

• Mouse Swiss Prot No：
• P97428

• Rat Swiss Prot No：
• P56700

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human RGS16 around the phosphorylation site of Tyr168. AA range:141-190

• 特异性：
• Phospho-RGS16 (Y168) Polyclonal Antibody detects endogenous levels of RGS16 protein only when phosphorylated at Y168.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• RGS16;RGSR;Regulator of G-protein signaling 16;RGS16;A28-RGS14P;Retinal-specific RGS;RGS-r;hRGS-r;Retinally abundant regulator of G-protein signaling

• 实测条带：
• 30kD

• 背景：
• The protein encoded by this gene belongs to the 'regulator of G protein signaling' family. It inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. [provided by RefSeq, Jul 2008],

• 功能：
• function:Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha. May play a role in regulating the kinetics of signaling in the phototransduction cascade.,PTM:Palmitoylated on Cys-2 and/or Cys-12.,PTM:Phosphorylation on Tyr-168 upon EGFR stimulation. Enhanced GTPase accelerating (GAP) activity on G(i)-alpha.,similarity:Contains 1 RGS domain.,tissue specificity:Abundantly expressed in retina with lower levels of expression in most other tissues.,

• 细胞定位：
• Membrane ; Lipid-anchor .

• 组织表达：
• Abundantly expressed in retina with lower levels of expression in most other tissues.

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