• 靶点：
• Tubulin α

• 简介：
• >>Phagosome;>>Apoptosis;>>Tight junction;>>Gap junction;>>Alzheimer disease;>>Parkinson disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Pathogenic Escherichia coli infection;>>Salmonella infection

• 基因名称：
• TUBA1B

• 蛋白名称：
• Tubulin alpha-1B chain (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain)

• Human Gene Id：
• 7277

• Human Swiss Prot No：
• P68363

• Mouse Swiss Prot No：
• P05213

• Rat Swiss Prot No：
• Q6P9V9

• 特异性：
• endogenous

• 组成：
• PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• 来源：
• Monoclonal, rabbit, IgG, Kappa

• 稀释：
• IHC 1:200-1:1000,WB 1:1000-1:5000,IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200,

• 纯化工艺：
• Protein A

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• Tubulin alpha-1B chain (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain)

• 分子量：
• 50kD

• 实测条带：
• 50kD

• 背景：
• function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.,PTM:Undergoes a tyrosination/detyrosination cycle, the cyclic removal and re-addition of a C-terminal tyrosine residue by the enzymes tubulin tyrosine carboxypeptidase (TTCP) and tubulin tyrosine ligase (TTL), respectively.,similarity:Belongs to the tubulin family.,subunit:Dimer of alpha and beta chains.,

• 功能：
• function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.,PTM:Undergoes a tyrosination/detyrosination cycle, the cyclic removal and re-addition of a C-terminal tyrosine residue by the enzymes tubulin tyrosine carboxypeptidase (TTCP) and tubulin tyrosine ligase (TTL), respectively.,similarity:Belongs to the tubulin family.,subunit:Dimer of alpha and beta chains.,

• 细胞定位：
• Cytoplasm

• 组织表达：
• Brain,Cajal-Retzius cell,Colon,Embryonic kidney,Eye,Fetal brain cortex,Keratinocyte

Protective effect of Cistanche deserticola on gentamicin-induced nephrotoxicity in rats Chinese Herbal Medicines Rui-bin Bai, Jing-min Fan, Yan-ping Wang, Yan Wang, Xue Li, Fang-di Hu WB Rat kidney
货号：YM8126

HDAC-selective Inhibitor Cay10603 Has Single Anti-tumour Effect in Burkitt’s Lymphoma Cells by Impeding the Cell Cycle. Current Medical Science 2019 Aug 05 WB Human CA46 cell, Raji Cell
货号：YM8126

Bawei Chenxiang Wan Ameliorates Cardiac Hypertrophy by Activating AMPK/PPAR-α Signaling Pathway Improving Energy Metabolism. Frontiers in Pharmacology Front Pharmacol. 2021 Jun;0:1314 WB Rat Myocardial tissue
货号：YM8126

杨慧丽, 陈星宇, and 郑维红. "n 氧化应激通过激活 Cdk5 抑制 FOXO1 的 神经元损伤及其机制." Journal of Xi'an Jiaotong University (Medical Sciences) 40.3 (2019).
货号：YM8126

Bawei Chenxiang Wan Ameliorates Cardiac Hypertrophy by Activating AMPK/PPAR-α Signaling Pathway Improving Energy Metabolism. Frontiers in Pharmacology Front Pharmacol. 2021 Jun;0:1314 WB Rat Myocardial tissue
货号：YM8126

Wang, Nuan, et al. "MARCH1 Interacts with β-Catenin as a New Oncogene for Gastric Cancer." (2021).
货号：YM8126

杨慧丽, 陈星宇, and 郑维红. "n 氧化应激通过激活 Cdk5 抑制 FOXO1 的 神经元损伤及其机制." Journal of Xi'an Jiaotong University (Medical Sciences) 40.3 (2019).
货号：YM8126

Bawei Chenxiang Wan Ameliorates Cardiac Hypertrophy by Activating AMPK/PPAR-α Signaling Pathway Improving Energy Metabolism. Frontiers in Pharmacology Front Pharmacol. 2021 Jun;0:1314 WB Rat Myocardial tissue
货号：YM8126

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