• 蛋白名称：
• STIM1 GOK

• 序列：
• Stromal interaction molecule 1

• Human Gene Id：
• 6786

• Human Swiss Prot No：
• Q13586

• Mouse Gene Id：
• 20866

• Mouse Swiss Prot No：
• P70302

• Rat Gene Id：
• 361618

• Rat Swiss Prot No：
• P84903

• 特异性：
• endogenous

• 组成：
• PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• 来源：
• Monoclonal, rabbit, IgG, Kappa

• 稀释：
• IHC 1:200-1:1000,WB 1:1000-1:5000,IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200,

• 纯化工艺：
• Protein A

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• Stromal interaction molecule 1

• 分子量：
• 77kD

• 实测条带：
• 77kD

• 功能：
• Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores . Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit ORAI1 . Involved in enamel formation . Activated following interaction with STIMATE, leading to promote STIM1 conformational switch .

• 细胞定位：
• Membrane

• 组织表达：
• Ubiquitously expressed in various human primary cells and tumor cell lines.

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