• 靶点：
• CA IX

• 简介：
• >>Nitrogen metabolism;>>Metabolic pathways

• 基因名称：
• CA9

• 蛋白名称：
• Carbonic anhydrase 9

• Human Gene Id：
• 768

• Human Swiss Prot No：
• Q16790

• Mouse Gene Id：
• 230099

• Mouse Swiss Prot No：
• Q8VHB5

• 免疫原：
• Recombinant protein

• 特异性：
• This antibody detects endogenous levels of CA IX protein.

• 组成：
• The prediluted ready-to-use antibody is diluted in phosphate buffer saline containing stabilizing protein and 0.05% Proclin 300

• 来源：
• Mouse, Monoclonal/IgG

• 稀释：
• Ready to use for IHC

• 纯化工艺：
• The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

• 储存：
• 2°C to 8°C/1 year

• 其他名称：
• G250; MN; Carbonic anhydrase 9; Carbonate dehydratase IX; Carbonic anhydrase IX; CA-IX; CAIX; Membrane antigen MN; P54/58N; Renal cell carcinoma-associated antigen G250; RCC-associated antigen G250; pMW1

• 功能：
• catalytic activity:H(2)CO(3) = CO(2) + H(2)O.,cofactor:Zinc.,function:Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia.,induction:By hypoxia.,PTM:Asn-346 bears high-mannose type glycan structures.,similarity:Belongs to the alpha-carbonic anhydrase family.,subcellular location:Found on the surface microvilli and in the nucleus, particularly in nucleolus.,subunit:Forms oligomers linked by disulfide bonds.,tissue specificity:Expressed primarily in carcinoma cells lines. Expression is restricted to very few normal tissues and the most abundant expression is found in the epithelial cells of gastric mucosa.,

• 细胞定位：
• Membranous

• 组织表达：
• Expressed primarily in carcinoma cells lines. Expression is restricted to very few normal tissues and the most abundant expression is found in the epithelial cells of gastric mucosa.

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