• 靶点：
• CD9

• 简介：
• >>Hematopoietic cell lineage

• 基因名称：
• CD9

• 蛋白名称：
• CD9 antigen

• Human Gene Id：
• 928

• Human Swiss Prot No：
• P21926

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human CD9. AA range:100-200

• 特异性：
• This antibody detects endogenous levels of CD9.

• 组成：
• PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• 来源：
• Mouse, Monoclonal/IgG,kappa

• 稀释：
• WB 1:500 - 1:1000. ELISA 1:20000.

• 纯化工艺：
• Protein G

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• CD9;MIC3;TSPAN29;GIG2;CD9 antigen;5H9 antigen;Cell growth-inhibiting gene 2 protein;Leukocyte antigen MIC3;Motility-related protein;MRP-1;Tetraspanin-29;Tspan-29;p24;CD antigen CD9

• 分子量：
• 24kD

• 实测条带：
• 22kD

• 背景：
• This gene encodes a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis. [provided by RefSeq, Jan 2011],

• 功能：
• function:Involved in platelet activation and aggregation. Regulates paranodal junction formation. Involved in cell adhesion, cell motility and tumor metastasis. Required for sperm-egg fusion.,PTM:Protein exists in three forms with molecular masses between 22 and 27 kDa, and is known to carry covalently linked fatty acids.,similarity:Belongs to the tetraspanin (TM4SF) family.,subunit:Forms both disulfide-linked homodimers and higher homooligomers as well as heterooligomers with other members of the tetraspanin family. Associates with CR2/CD21 and with PTGFRN/CD9P1. Interacts directly with IGSF8.,tissue specificity:Expressed by a variety of hematopoietic and epithelial cells.,

• 细胞定位：
• Cell membrane ; Multi-pass membrane protein . Membrane ; Multi-pass membrane protein . Secreted, extracellular exosome . Present at the cell surface of oocytes. Accumulates in the adhesion area between the sperm and egg following interaction between IZUMO1 and its receptor IZUMO1R/JUNO. .

• 组织表达：
• Detected in platelets (at protein level) (PubMed:19640571). Expressed by a variety of hematopoietic and epithelial cells (PubMed:19640571).

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