• 靶点：
• Tubulin β II

• 简介：
• >>Phagosome;>>Gap junction;>>Alzheimer disease;>>Parkinson disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Pathogenic Escherichia coli infection;>>Salmonella infection

• 基因名称：
• TUBB2A

• 蛋白名称：
• Tubulin beta-2A chain

• Human Gene Id：
• 7280

• Human Swiss Prot No：
• Q13885

• Mouse Gene Id：
• 22151

• Mouse Swiss Prot No：
• Q7TMM9

• Rat Gene Id：
• 498736

• Rat Swiss Prot No：
• P85108

• 免疫原：
• Synthetic Peptide of β II tubulin

• 特异性：
• The antibody detects endogenous β II tubulin protein.

• 组成：
• PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

• 来源：
• Monoclonal, Mouse

• 稀释：
• WB 1:50000-100000 IP:1:200 IHC 1:50-300. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• Tubulin beta-2A chain

• 实测条带：
• 50kD

• 背景：
• Microtubules, key participants in processes such as mitosis and intracellular transport, are composed of heterodimers of alpha- and beta-tubulins. The protein encoded by this gene is a beta-tubulin. Defects in this gene are associated with complex cortical dysplasia with other brain malformations-5. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2015],

• 功能：
• function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.,similarity:Belongs to the tubulin family.,subunit:Dimer of alpha and beta chains.,

• 细胞定位：
• Cytoplasm, cytoskeleton .

• 组织表达：
• High expression in brain, where it represents 30% of all beta-tubulins.

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