COX IV Monoclonal Antibody(6C8), HRP Conjugated

  • 货号:YM2015
  • 应用:WB;IHC;IF;
  • 种属:Human;Rat;Mouse
    • 靶点:
    • COX IV
    • 简介:
    • >>Oxidative phosphorylation;>>Metabolic pathways;>>Cardiac muscle contraction;>>Thermogenesis;>>Non-alcoholic fatty liver disease;>>Alzheimer disease;>>Parkinson disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Chemical carcinogenesis - reactive oxygen species;>>Diabetic cardiomyopathy
    • 基因名称:
    • COX4I1
    • 蛋白名称:
    • Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
    • Human Gene Id:
    • 1327
    • Human Swiss Prot No:
    • P13073
    • 特异性:
    • COX IV Monoclonal Antibody(6C8) HRP Conjugated, specially designed for your Western blot analysis.
    • 组成:
    • Liquid in PBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% Glycerol.
    • 来源:
    • Monoclonal, Mouse IgG1
    • 稀释:
    • Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:1000-3000, IHC 1:50-300.
    • 纯化工艺:
    • The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
    • 浓度:
    • 1mg/ml
    • 储存:
    • Stable for one year at -15°C to -25°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezi
    • 其他名称:
    • COX4I1
    • 分子量:
    • 20kD
    • 背景:
    • Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes
    • 功能:
    • function:This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.,similarity:Belongs to the cytochrome c oxidase IV family.,tissue specificity:Ubiquitous.,
    • 细胞定位:
    • Mitochondrion inner membrane ; Single-pass membrane protein .
    • 组织表达:
    • Ubiquitous.

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    货号:YM2015

    Low-dose cadmium exposure acts on rat mesenchymal stem cells via RANKL/OPG and downregulate osteogenic differentiation genes. ENVIRONMENTAL POLLUTION 2019 Mar 15 FC Rat MSCs
    货号:YM2015

    Low-dose cadmium exposure acts on rat mesenchymal stem cells via RANKL/OPG and downregulate osteogenic differentiation genes. ENVIRONMENTAL POLLUTION 2019 Mar 15 FC Rat MSCs
    货号:YM2015