• 靶点：
• Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204)

• 基因名称：
• mapk

• Human Gene Id：
• /

• 免疫原：
• Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) synthetic peptide conjugated to KLH.

• 特异性：
• This antibody detects endogenous levels of Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204).

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Monoclonal, Mouse

• 稀释：
• wb dilution 1:500

• 纯化工艺：
• The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• ERK 1;ERK 2;ERK-2;ERK1;erk1/2;ERK2;ERT1;ERT2;Extracellular signal regulated kinase 1;Extracellular signal regulated kinase 1;Extracellular signal regulated kinase 2;Extracellular signal regulated kinase 2;Extracellular signal-regulated kinase 2;HS44KDAP;HUMKER1A;Insulin stimulated MAP2 kinase;MAP kinase 1;MAP kinase 2;MAP kinase isoform p42;MAP kinase isoform p44;MAPK 1;MAPK 2;MAPK 3;MAPK 3;MAPK1;MAPK2;MAPK3;MGC20180;Microtubule associated protein 2 kinase;Mitogen activated protein kinase 1;Mitogen activated protein kinase 1;Mitogen activated protein kinase 2;Mitogen activated protein kinase 3;Mitogen activated protein kinase 3;Mitogen-activated protein kinase 1;Mitogen-activated protein kinase 2;MK01_HUMAN;p38;p40;p41;p41mapk;p42 MAPK;p42-MAPK;p42MAPK;p42MAPK;p44 ERK1;p44 MAPK;p44ERK1;p44ERK1;p44MAPK;p44MAPK;PRKM 1;PRKM 1;PRKM 2;PRKM 2;PRKM 3;PRKM 3;PRKM1;PRKM2;PRKM3;Protein kinase mitogen activated 1;Protein kinase mitogen activated 1;Protein kinase mitogen activated 2;Protein kinase

• 实测条带：
• 44/42kD

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货号：YM1464

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Network Pharmacology-Based Strategy to Identify the Pharmacological Mechanisms of Pulsatilla Decoction against Crohn's Disease.. Frontiers in Pharmacology2022 Apr;13:844685-844685. Human,Mouse 1:1000 colon tissues
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CXCL3 overexpression promotes the tumorigenic potential of uterine cervical cancer cells via the MAPK/ERK pathway. JOURNAL OF CELLULAR PHYSIOLOGY J Cell Physiol. 2020 May;235(5):4756-4765 WB Human 1:1000 HeLa cell
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Honokiol-mesoporous Silica Nanoparticles Inhibit Vascular Restenosis via the Suppression of TGF-β Signaling Pathway. International Journal of Nanomedicine Int J Nanomed. 2020; 15: 5239–5252 WB Rat Vascular smooth muscle cells （VSMCs）
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PM2.5 induces autophagy-mediated cell death via NOS2 signaling in human bronchial epithelium cells. International Journal of Biological Sciences Int J Biol Sci. 2018; 14(5): 557–564 WB Human
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Administration of SB203580, a p38 MAPK Inhibitor, Reduced the Expression of MMP9, and Relieved Neurologic Severity in the Experimental Autoimmune Neuritis (EAN) in Rats. NEUROCHEMICAL RESEARCH Neurochem Res. 2015 Jul;40(7):1410-1420 WB Rat 1:1000 sciatic nerves
货号：YM1464

The mechanism of mulberry leaves against renal tubular interstitial fibrosis through ERK1/2 signaling pathway was predicted by network pharmacology and validated in human tubular epithelial cells. PHYTOTHERAPY RESEARCH 2019 Jun 17 WB Human 1:1000 HK-2 cell
货号：YM1464

The antitumor effect of hinesol, extract from Atractylodes lancea (Thunb.) DC. by proliferation, inhibition, and apoptosis induction via MEK/ERK and NF‐κB pathway in non–small cell lung cancer cell lines A549 and NCI‐H1299. JOURNAL OF CELLULAR BIOCHEMISTRY 2019 Jul 24 WB Human A549 cell
货号：YM1464

HMGB1 binding to receptor for advanced glycation end products enhances inflammatory responses of human bronchial epithelial cells by activating p38 MAPK and ERK1/2. MOLECULAR AND CELLULAR BIOCHEMISTRY Mol Cell Biochem. 2015 Jul;405(1):63-71 WB Human HBECs
货号：YM1464

Poly-L-Arginine Induces Apoptosis of NCI-H292 Cells via ERK1/2 Signaling Pathway. Journal of Immunology Research J Immunol Res. 2018;2018:3651743 WB Human 1 : 500 NCI-H292 cell
货号：YM1464

Inhibitory effects of oxymatrine on TGF‑β1‑induced proliferation and abnormal differentiation in rat cardiac fibroblasts via the p38MAPK and ERK1/2 signaling pathways. Molecular Medicine Reports Mol Med Rep. 2017 Oct;16(4):5354-5362 WB Rat 1:1000 cardiac fibroblast (CFB)
货号：YM1464

Reactive oxygen species regulatory mechanisms associated with rapid response of MC3T3-E1 cells for vibration stress. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2016 Jan 21 WB Human 1:1000 MC3T3-E1 cell
货号：YM1464

SCF/C-KIT signaling modulates tryptase expression in acute myeloid leukemia cells. INTERNATIONAL JOURNAL OF HEMATOLOGY Int J Hematol. 2014 Jun;99(6):750-757 WB Human U937 cell
货号：YM1464

MiR-21-5p ameliorates Busulfan-induced testicular dysfunction and maintains spermatogenesis1 Journal of Integrative Agriculture Meng-fei ZHANG WB Goat Male germ stem cells (mGSCs)
货号：YM1464

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