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Tubulin β Monoclonal Antibody

货号：YM1110
应用：WB;IP
种属：Human;Mouse;Rat;Bovine;Rabbit

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靶点：
Tubulin β

简介：
>>Phagosome;>>Gap junction;>>Alzheimer disease;>>Parkinson disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Pathogenic Escherichia coli infection;>>Salmonella infection

基因名称：
TUBB1

蛋白名称：
Tubulin beta-1 chain

Human Gene Id：
81027

Human Swiss Prot No：
P07437

Mouse Gene Id：
545486

Mouse Swiss Prot No：
A2AQ07

免疫原：
Purified recombinant human Tubulin β protein fragments expressed in E.coli.

特异性：
Tubulin β Monoclonal Antibody detects endogenous levels of Tubulin β protein.

组成：
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

来源：
Monoclonal, Mouse

稀释：
WB 1:1000 - 1:2000. Not yet tested in other applications.

纯化工艺：
Affinity purification

浓度：
1 mg/ml

储存：
-15°C to -25°C/1 year(Do not lower than -25°C)

其他名称：
TUBB1;Tubulin beta-1 chain

分子量：
50kD

背景：
This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.[provided by RefSeq, Jul 2010],

功能：
function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.,similarity:Belongs to the tubulin family.,subunit:Dimer of alpha and beta chains.,

细胞定位：
Cytoplasm, cytoskeleton .

组织表达：
Hematopoietic cell-specific. Major isotype in leukocytes, where it represents 50% of all beta-tubulins.

Tanshinone IIA attenuates paraquat‑induced acute lung injury by modulating angiotensin‑converting enzyme 2/angiotensin‑(1‑7) in rats. Molecular Medicine Reports Mol Med Rep. 2018 Sep;18(3):2955-2962 WB Rat lung tissues
货号：YM1110

RILP inhibits proliferation, migration, and invasion of PC3 prostate cancer cells ACTA HISTOCHEMICA Guoxiang Wang WB Human
货号：YM1110