KLHL21 Monoclonal Antibody
- 货号：YM0402
- 应用：WB;IHC;IF;ELISA
- 种属：Human
- 蛋白名称：
- Kelch-like protein 21
- 免疫原：
- Purified recombinant fragment of human KLHL21 expressed in E. Coli.
- 特异性：
- KLHL21 Monoclonal Antibody detects endogenous levels of KLHL21 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 稀释：
- WB 1:500 - 1:2000. IHC 1:200 - 1:1000. ELISA: 1:10000.. IF 1:50-200
- 纯化工艺：
- Affinity purification
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- KLHL21;KIAA0469;Kelch-like protein 21
- 背景：
- function:Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 BACK (BTB/Kelch associated) domain.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 6 Kelch repeats.,subunit:Interacts with cul3.,
- 功能：
- function:Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 BACK (BTB/Kelch associated) domain.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 6 Kelch repeats.,subunit:Interacts with cul3.,
- 细胞定位：
- Cytoplasm, cytoskeleton, spindle . Localizes to the spindle midzone and targets CUL3 to this region.
- 组织表达：
- Brain,Hepatoma,Hippocampus,Lung carcinoma,PCR rescued clones,Spleen,
- Western Blot analysis using KLHL21 Monoclonal Antibody against recombinant KLHL21 protein (1).
- Immunohistochemistry analysis of paraffin-embedded human brain tissues with DAB staining using KLHL21 Monoclonal Antibody.
