• 靶点：
• Blimp-1

• 基因名称：
• PRDM1

• 蛋白名称：
• PR domain zinc finger protein 1

• Human Gene Id：
• 639

• Human Swiss Prot No：
• O75626

• Mouse Gene Id：
• 12142

• Mouse Swiss Prot No：
• Q60636

• 免疫原：
• Purified recombinant fragment of human Blimp-1 expressed in E. Coli.

• 特异性：
• Blimp-1 Monoclonal Antibody detects endogenous levels of Blimp-1 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Monoclonal, Mouse

• 稀释：
• WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

• 纯化工艺：
• Affinity purification

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• PRDM1;BLIMP1;PR domain zinc finger protein 1;BLIMP-1;Beta-interferon gene positive regulatory domain I-binding factor;PR domain-containing protein 1;Positive regulatory domain I-binding factor 1;PRDI-BF1;PRDI-binding factor 1

• 分子量：
• 92kD

• 背景：
• This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported. [provided by RefSeq, Jul 2008],

• 功能：
• function:Transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells.,similarity:Contains 1 SET domain.,similarity:Contains 4 C2H2-type zinc fingers.,subunit:Interacts with PRMT5.,

• 细胞定位：
• Nucleus . Cytoplasm .

• 组织表达：
• PCR rescued clones,Stomach,

Effect of Enterococcus faecalis on osteoclastogenesis under cobalt-mimicked hypoxia in vitro MICROBIAL PATHOGENESIS Fengyi Zhou, Xin Li, Xiaochi Chang, Zhihao Geng, Wenjing Hao, Jing Deng, Hai Ming Wong, Shuai Wang WB Mouse BMMs
货号：YM0063

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