• 靶点：
• MYH-pan

• 基因名称：
• MYH1

• 蛋白名称：
• MYH-pan (Acetyl Lys505)

• Human Gene Id：
• 4619

• Human Swiss Prot No：
• P12882/Q9UKX2/P11055/Q9Y623/P13533/P12883/P13535

• Mouse Gene Id：
• 17879

• Mouse Swiss Prot No：
• Q5SX40

• 免疫原：
• Synthesized peptide derived from human MYH-pan (Acetyl Lys505)

• 特异性：
• This antibody detects endogenous levels of Human,Mouse,Rat MYH-pan (Acetyl Lys505)

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

• 纯化工艺：
• The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• Myosin-1 (Myosin heavy chain 1;Myosin heavy chain 2x;MyHC-2x;Myosin heavy chain IIx/d;MyHC-IIx/d;Myosin heavy chain, skeletal muscle, adult 1)

• 实测条带：
• 77kD

• 背景：
• Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is a hexameric protein composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. Myosin heavy chains are encoded by a multigene family. In mammals at least 10 different myosin heavy chain (MYH) isoforms have been described from striated, smooth, and nonmuscle cells. These isoforms show expression that is spatially and temporally regulated during development. [provided by RefSeq, Jul 2008],

• 功能：
• domain:The rodlike tail sequence is highly repetitive, showing cycles of a 28-residue repeat pattern composed of 4 heptapeptides, characteristic for alpha-helical coiled coils.,function:Muscle contraction.,miscellaneous:Each myosin heavy chain can be split into 1 light meromyosin (LMM) and 1 heavy meromyosin (HMM). It can later be split further into 2 globular subfragments (S1) and 1 rod-shaped subfragment (S2).,similarity:Contains 1 IQ domain.,similarity:Contains 1 myosin head-like domain.,subcellular location:Thick filaments of the myofibrils.,subunit:Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2).,

• 细胞定位：
• Cytoplasm, myofibril. Thick filaments of the myofibrils.

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