Cleaved-Cathepsin Z (L62) Polyclonal Antibody
- 货号：YC0046
- 应用：WB;ELISA
- 种属：Human;Monkey
- 简介：
- >>Lysosome;>>Apoptosis
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human CATZ. AA range:43-92
- 特异性：
- Cleaved-Cathepsin Z (L62) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin Z protein resulting from cleavage adjacent to L62.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- CTSZ;Cathepsin Z;Cathepsin P;Cathepsin X
- 背景：
- The protein encoded by this gene is a lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. The encoded protein has also been known as cathepsin X and cathepsin P. This gene is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis. [provided by RefSeq, Oct 2008],
- 功能：
- catalytic activity:Release of C-terminal amino acid residues with broad specificity, but lacks action on C-terminal proline. Shows weak endopeptidase activity.,function:Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity.,similarity:Belongs to the peptidase C1 family.,tissue specificity:Widely expressed.,
- Western Blot analysis of various cells using Cleaved-Cathepsin Z (L62) Polyclonal Antibody
- Western blot analysis of lysates from COS7 cells, treated with etoposide 25uM 1h, using CATZ (Cleaved-Leu62) Antibody. The lane on the right is blocked with the synthesized peptide.
