- 靶点：
- Cathepsin H
- 简介：
- >>Lysosome;>>Apoptosis
- 基因名称：
- CTSH
- 蛋白名称：
- Pro-cathepsin H
- Human Gene Id：
- 1512
- Human Swiss Prot No：
- P09668
- Mouse Swiss Prot No：
- P49935
- 免疫原：
- Synthesized peptide derived from Cathepsin H . at AA range: 70-150
- 特异性：
- Cathepsin H Polyclonal Antibody detects endogenous levels of Cathepsin H protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. ELISA: 1:20000.. IF 1:50-200
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 浓度：
- 1 mg/ml
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- CTSH;CPSB;Pro-cathepsin H
- 实测条带：
- 40kD
- 背景：
- The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016],
- 功能：
- catalytic activity:Hydrolysis of proteins, acting as an aminopeptidase (notably, cleaving Arg-|-Xaa bonds) as well as an endopeptidase.,function:Important for the overall degradation of proteins in lysosomes.,similarity:Belongs to the peptidase C1 family.,subunit:Composed of a mini chain and a large chain. The large chain may be split into heavy and light chain. All chains are held together by disulfide bonds.,
- 细胞定位：
- Lysosome.
- 组织表达：
- Cartilage,Eye,Kidney,Liver,Lung,Salivary gland,
Machine-learning and combined analysis of single-cell and bulk-RNA sequencing identified a DC gene signature to predict prognosis and immunotherapy response for patients with lung adenocarcinoma. Lai Fancai WB Human 1:1000 lung adenocarcinoma (LUAD) tissue BEAS-2B cell,A549 cell,HCC827 cell,H1975 cell
货号：YC0040
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- Antibody-FAQs
- 产品图片
- Immunofluorescence analysis of Caco2 cell. 1,primary Antibody was diluted at 1:100(4°C overnight). 2, Goat Anti Rabbit IgG (H&L) - AFluor 594 Secondary antibody(catalog No: RS3611) was diluted at 1:500(room temperature, 50min).
- Western Blot analysis of various cells using Cathepsin H Polyclonal Antibody
