Total LIMK1 Cell-Based Colorimetric ELISA Kit

  • 货号:KA4338C
  • 应用:ELISA
  • 种属:Human;Mouse;Rat
    • 基因名称:
    • LIMK1
    • Human Gene Id:
    • 3984
    • Human Swiss Prot No:
    • P53667
    • Mouse Swiss Prot No:
    • P53668
    • 储存:
    • 2-8°C/6 months
    • 其他名称:
    • LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1)
    • 检测方法:
    • Colorimetric
    • 功能:
    • regulation of cell growth, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, cytoskeleton organization, intracellular signaling cascade, small GTPase mediated signal transduction, Ras protein signal transduction, Rho protein signal transduction, regulation of cell size, positive regulation of cell development, regulation of cell morphogenesis involved in differentiation, regulation of neuron projection development, phosphorylation, regulation of cell morphogenesis, actin filament-based process, actin cytoskeleton organization, positive regulation of cell growth, regulation of axon extension, regulation of cell projection organization,positive regulation of cell projection organization, regulation of cellular component size, regulation of growth, positive regulation of cell differentiation, regulation of neuron differentiation, positive regulat
    • 细胞定位:
    • Cytoplasm . Nucleus . Cytoplasm, cytoskeleton . Cell projection, lamellipodium . Predominantly found in the cytoplasm. Localizes in the lamellipodium in a CDC42BPA, CDC42BPB and FAM89B/LRAP25-dependent manner. .
    • 组织表达:
    • Highest expression in both adult and fetal nervous system. Detected ubiquitously throughout the different regions of adult brain, with highest levels in the cerebral cortex. Expressed to a lesser extent in heart and skeletal muscle.

    Alantolactone suppresses the metastatic phenotype and induces the apoptosis of glioblastoma cells by targeting LIMK kinase activity and activating the cofilin/G‑actin signaling cascade. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE Int J Mol Med. 2021 May;47(5):1-13 ELISA Human U87MG cell,U251 cells
    货号:KA4338C