Total SEK1/MKK4 Cell-Based Colorimetric ELISA Kit

  • 货号:KA4273C
  • 应用:ELISA
  • 种属:Human;Mouse;Rat
    • 基因名称:
    • MAP2K4
    • Human Gene Id:
    • 6416
    • Human Swiss Prot No:
    • P45985
    • Mouse Swiss Prot No:
    • P47809
    • 储存:
    • 2-8°C/6 months
    • 其他名称:
    • Dual specificity mitogen-activated protein kinase kinase 4 (MAP kinase kinase 4) (MAPKK 4) (EC 2.7.12.2) (JNK-activating kinase 1) (MAPK/ERK kinase 4) (MEK 4) (SAPK/ERK kinase 1) (SEK1) (Stress-activated protein kinase kinase 1) (SAPK kinase 1) (SAPKK-1) (SAPKK1) (c-Jun N-terminal kinase kinase 1) (JNKK)
    • 检测方法:
    • Colorimetric
    • 背景:
    • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Dual specificity kinase that activates the JUN kinases MAPK8 (JNK1) and MAPK9 (JNK2) as well as MAPK14 (p38) but not MAPK1 (ERK2) or MAPK3 (ERK1).,PTM:Activated by phosphorylation on Ser/Thr by MAP kinase kinase kinases.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with SPAG9.,tissue specificity:Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.,
    • 功能:
    • MAPKKK cascade, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process,intracellular signaling cascade, protein kinase cascade, JNK cascade, phosphorylation, stress-activated protein kinase signaling pathway, cellular response to stress,
    • 细胞定位:
    • Cytoplasm . Nucleus .
    • 组织表达:
    • Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.