Total PBK/TOPK Cell-Based Colorimetric ELISA Kit
- 货号：KA4222C
- 应用：ELISA
- 种属：Human
- 其他名称：
- Lymphokine-activated killer T-cell-originated protein kinase (EC 2.7.12.2) (Cancer/testis antigen 84) (CT84) (MAPKK-like protein kinase) (Nori-3) (PDZ-binding kinase) (Spermatogenesis-related protein kinase) (SPK) (T-LAK cell-originated protein kinase)
- 背景：
- catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Activated by phosphorylation.,function:Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage.,PTM:Phosphorylated; in a cell-cycle dependent manner at mitosis.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase kinase subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with DLG1 and TP53.,tissue specificity:Expressed in the testis and placenta. In the testis, restrictedly expressed in outer cell layer of seminiferous tubules.,
- 功能：
- M phase of mitotic cell cycle, mitotic cell cycle, M phase, nuclear division, protein amino acid phosphorylation,phosphorus metabolic process, phosphate metabolic process, cell cycle, mitosis, phosphorylation, cell cycle process,cell cycle phase, organelle fission,
- 组织表达：
- Expressed in the testis and placenta. In the testis, restrictedly expressed in outer cell layer of seminiferous tubules.
