Total Opioid Receptor Cell-Based Colorimetric ELISA Kit

  • 货号：KA4205C
  • 应用：ELISA
  • 种属：Human;Mouse;Rat
    • 基因名称：
    • OPRM1
    • Human Gene Id：
    • 4988
    • Human Swiss Prot No：
    • P35372
    • Mouse Swiss Prot No：
    • P42866
    • 储存：
    • 2-8°C/6 months
    • 其他名称：
    • Mu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid receptor) (MOP) (hMOP)
    • 检测方法：
    • Colorimetric
    • 背景：
    • function:Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Receptor for beta-endorphin.,online information:Mu opioid receptor entry,polymorphism:Variant Asp-40 does not show altered binding affinities for most opioid peptides and alkaloids tested, but it binds beta-endorphin, an endogenous opioid that activates the mu opioid receptor, approximately 3 times more tightly than the most common allelic form.,similarity:Belongs to the G-protein coupled receptor 1 family.,subunit:Forms a complex with G(alpha)z/i2 subunits and the RGSZ proteins, RGSZ17 and RGSZ20. The formation of this complex results in mu-opioid receptor desensitization. Interacts with RGSZ17 and RGSZ20.,
    • 功能：
    • regulation of nucleotide metabolic process, cell surface receptor linked signal transduction, G-protein coupled receptor protein signaling pathway, G-protein signaling, coupled to cyclic nucleotide second messenger, G-protein signaling, coupled to cAMP nucleotide second messenger, activation of adenylate cyclase activity by G-protein signaling pathway,activation of adenylate cyclase activity, activation of adenylate cyclase activity by dopamine receptor signaling pathway, inhibition of adenylate cyclase activity by G-protein signaling, negative regulation of adenylate cyclase activity, dopamine receptor signaling pathway, intracellular signaling cascade, sensory perception, behavior,locomotory behavior, negative regulation of cell proliferation, regulation of adenylate cyclase activity involved in G-protein signaling, positive regulation of adenylate cyclase activity by G-protein signali
    • 细胞定位：
    • Cell membrane ; Multi-pass membrane protein . Cell projection, axon . Perikaryon . Cell projection, dendrite . Endosome . Is rapidly internalized after agonist binding. .; [Isoform 12]: Cytoplasm .
    • 组织表达：
    • Expressed in brain. Isoform 16 and isoform 17 are detected in brain.

    相关报价

    • 货号：
    • KA4205C
    • 规格：
    • 96 / well
    • 价格：
    • ¥3300
    • 货期：
    • 预计发货时间为
      2024-12-08
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