Total MAK Cell-Based Colorimetric ELISA Kit
- 货号：KA4163C
- 应用：ELISA
- 种属：Human;Mouse;Rat
- 其他名称：
- Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male germ cell-associated kinase)
- 背景：
- catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Could play an important function in spermatogenesis.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed mainly in testicular cells at and after meiosis.,
- 功能：
- protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, gamete generation,spermatogenesis, phosphorylation, sexual reproduction, multicellular organism reproduction, male gamete generation,reproductive process in a multicellular organism,
- 细胞定位：
- Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Midbody. Cell projection, cilium, photoreceptor outer segment . Photoreceptor inner segment. Localized in both the connecting cilia and the outer segment axonemes (By similarity). Localized uniformly in nuclei during interphase, to the mitotic spindle and centrosomes during metaphase and anaphase, and also to midbody at anaphase until telophase. .
- 组织表达：
- Expressed in prostate cancer cell lines at generally higher levels than in normal prostate epithelial cell lines. Isoform 1 is expressed in kidney, testis, lung, trachea, and retina. Isoform 2 is retina-specific where it is expressed in rod and cone photoreceptors.
