Total IL-3Rβ Cell-Based Colorimetric ELISA Kit
- 货号:KA4136C
- 应用:ELISA
- 种属:Human;Mouse;Rat
- 基因名称:
- CSF2RB
- Human Gene Id:
- 1439
- Human Swiss Prot No:
- P32927
- Mouse Swiss Prot No:
- P26955
- 储存:
- 2-8°C/6 months
- 其他名称:
- Cytokine receptor common subunit beta (CDw131) (GM-CSF/IL-3/IL-5 receptor common beta subunit) (CD antigen CD131)
- 检测方法:
- Colorimetric
- 背景:
- disease:Defects in CSF2RB are a cause of congenital pulmonary alveolar proteinosis (PAP) [MIM:265120]. PAP is an autosomal recessive fatal respiratory disease.,domain:The box 1 motif is required for JAK interaction and/or activation.,domain:The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.,function:High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.,similarity:Belongs to the type I cytokine receptor family. Type 4 subfamily.,similarity:Contains 2 fibronectin type-III domains.,subunit:Heterodimer of an alpha and a beta subunit. The beta subunit is common to the IL3, IL5 and GM-CSF receptors.,
- 功能:
- respiratory gaseous exchange, cytokine-mediated signaling pathway,
- 细胞定位:
- Membrane; Single-pass type I membrane protein.
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