Total IL-3Rβ Cell-Based Colorimetric ELISA Kit

  • 货号:KA4136C
  • 应用:ELISA
  • 种属:Human;Mouse;Rat
    • 基因名称:
    • CSF2RB
    • Human Gene Id:
    • 1439
    • Human Swiss Prot No:
    • P32927
    • Mouse Swiss Prot No:
    • P26955
    • 储存:
    • 2-8°C/6 months
    • 其他名称:
    • Cytokine receptor common subunit beta (CDw131) (GM-CSF/IL-3/IL-5 receptor common beta subunit) (CD antigen CD131)
    • 检测方法:
    • Colorimetric
    • 背景:
    • disease:Defects in CSF2RB are a cause of congenital pulmonary alveolar proteinosis (PAP) [MIM:265120]. PAP is an autosomal recessive fatal respiratory disease.,domain:The box 1 motif is required for JAK interaction and/or activation.,domain:The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.,function:High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.,similarity:Belongs to the type I cytokine receptor family. Type 4 subfamily.,similarity:Contains 2 fibronectin type-III domains.,subunit:Heterodimer of an alpha and a beta subunit. The beta subunit is common to the IL3, IL5 and GM-CSF receptors.,
    • 功能:
    • respiratory gaseous exchange, cytokine-mediated signaling pathway,
    • 细胞定位:
    • Membrane; Single-pass type I membrane protein.