Total IL-2Rα Cell-Based Colorimetric ELISA Kit
- 货号：KA4134C
- 应用：ELISA
- 种属：Human
- 其他名称：
- Interleukin-2 receptor subunit alpha (IL-2 receptor subunit alpha) (IL-2-RA) (IL-2R subunit alpha) (IL2-RA) (TAC antigen) (p55) (CD antigen CD25)
- 背景：
- disease:Genetic variations in IL2RA are associated with susceptibility to insulin-dependent diabetes mellitus type 10 (IDDM10) [MIM:601942].,function:Receptor for interleukin-2.,online information:IL2RA mutation db,similarity:Contains 2 Sushi (CCP/SCR) domains.,subunit:Non-covalent dimer of an alpha and a beta chains. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta chain), and a low affinity monomer (alpha chain). The high and intermediate affinity forms also associate with a gamma chain.,
- 功能：
- leukocyte homeostasis, lymphocyte homeostasis, inflammatory response to antigenic stimulus, negative regulation of immune system process, positive regulation of immune system process, regulation of leukocyte activation, negative regulation of leukocyte activation, positive regulation of leukocyte activation, apoptosis, activation-induced cell death of T cells, defense response, inflammatory response, immune response, cell surface receptor linked signal transduction, cell death, cell proliferation, positive regulation of cell proliferation, negative regulation of cell proliferation, response to wounding, regulation of cell death, positive regulation of cell death, programmed cell death,death, negative regulation of defense response, regulation of response to external stimulus, negative regulation of response to external stimulus, regulation of homeostatic process, regulation of mononuclea
- 细胞定位：
- Membrane; Single-pass type I membrane protein.
