Cleaved-SUMO-2/3 (G93) Cell-Based Colorimetric ELISA Kit

  • 货号：KA3976C
  • 应用：ELISA
  • 种属：Human;Mouse;Rat
    • 基因名称：
    • SUMO2
    • Human Gene Id：
    • 6613
    • Human Swiss Prot No：
    • P61956
    • Mouse Swiss Prot No：
    • P61957
    • 储存：
    • 2-8°C/6 months
    • 其他名称：
    • Small ubiquitin-related modifier 2 (SUMO-2) (HSMT3) (SMT3 homolog 2) (SUMO-3) (Sentrin-2) (Ubiquitin-like protein SMT3A) (Smt3A)
    • 检测方法：
    • Colorimetric
    • 背景：
    • function:Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4.,online information:SUMO protein entry,PTM:Cleavage of precursor form by SENP1 or SENP2 is necessary for function.,PTM:Cleavage of precursor form by SENP1, SENP2 or SENP5 is necessary for function.,PTM:Polymeric chains can be formed through Lys-11 cross-linking.,similarity:Belongs to the ubiquitin family. SUMO subfamily.,similarity:Contains 1 ubiquitin-like domain.,subcellular location:Nuclear bodies.,subunit:Homotrimer (Potential). Crystal packing analysis suggests a possible trimeric assembly, of which the biological significance remains to be determined. Interacts with SAE2 and UBE2I. Covalently attached to a number of proteins. Interacts with PELP1.,subunit:Interacts with SAE2 and UBE2I. Covalently attached to a number of proteins.,tissue specificity:Broadly expressed.,tissue specificity:Expressed predominantly in liver.,
    • 功能：
    • proteolysis, macromolecule catabolic process, protein sumoylation, modification-dependent protein catabolic process,protein catabolic process, protein modification by small protein conjugation, modification-dependent macromolecule catabolic process, cellular protein catabolic process, cellular macromolecule catabolic process, proteolysis involved in cellular protein catabolic process, protein modification by small protein conjugation or removal,
    • 细胞定位：
    • Nucleus. Nucleus, PML body.
    • 组织表达：
    • Broadly expressed.

    相关报价

    • 货号：
    • KA3976C
    • 规格：
    • 96 / well
    • 价格：
    • ¥3300
    • 货期：
    • 预计发货时间为
      2024-08-07
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