Total CYP3A43 Cell-Based Colorimetric ELISA Kit
- 货号:KA3897C
- 应用:ELISA
- 种属:Human
- 其他名称:
- Cytochrome P450 3A43 (EC 1.14.14.1)
- 背景:
- alternative products:Additional isoforms seem to exist,catalytic activity:RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O.,cofactor:Heme group.,function:Exhibits low testosterone 6-beta-hydroxylase activity.,induction:By rifampicin.,online information:CYP3A43 alleles,polymorphism:At protein level, three alleles are known: CYP3A43*1, CYP3A43*2 and CYP3A43*3. The sequence shown is that of CYP3A43*1, which is the most frequent allele. The allele CYP3A43*2 is likely to be non-functional.,similarity:Belongs to the cytochrome P450 family.,tissue specificity:Highest expression level in prostate. Also expressed in liver, kidney, pancreas, fetal liver and fetal skeletal muscle.,
- 细胞定位:
- Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
- 组织表达:
- Highest expression level in prostate. Also expressed in liver, kidney, pancreas, fetal liver and fetal skeletal muscle.