Total CYP3A43 Cell-Based Colorimetric ELISA Kit

  • 货号:KA3897C
  • 应用:ELISA
  • 种属:Human
    • 基因名称:
    • CYP3A43
    • Human Swiss Prot No:
    • Q9HB55
    • 储存:
    • 2-8°C/6 months
    • 其他名称:
    • Cytochrome P450 3A43 (EC 1.14.14.1)
    • 检测方法:
    • Colorimetric
    • 背景:
    • alternative products:Additional isoforms seem to exist,catalytic activity:RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O.,cofactor:Heme group.,function:Exhibits low testosterone 6-beta-hydroxylase activity.,induction:By rifampicin.,online information:CYP3A43 alleles,polymorphism:At protein level, three alleles are known: CYP3A43*1, CYP3A43*2 and CYP3A43*3. The sequence shown is that of CYP3A43*1, which is the most frequent allele. The allele CYP3A43*2 is likely to be non-functional.,similarity:Belongs to the cytochrome P450 family.,tissue specificity:Highest expression level in prostate. Also expressed in liver, kidney, pancreas, fetal liver and fetal skeletal muscle.,
    • 功能:
    • oxidation reduction,
    • 细胞定位:
    • Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
    • 组织表达:
    • Highest expression level in prostate. Also expressed in liver, kidney, pancreas, fetal liver and fetal skeletal muscle.