• 基因名称：
• CYP2J2

• Human Gene Id：
• 1573

• Human Swiss Prot No：
• P51589

• 储存：
• 2-8°C/6 months

• 其他名称：
• Cytochrome P450 2J2 (EC 1.14.14.1) (Arachidonic acid epoxygenase) (CYPIIJ2)

• 检测方法：
• Colorimetric

• 背景：
• catalytic activity:RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O.,cofactor:Heme group.,function:This enzyme metabolizes arachidonic acid predominantly via a NADPH-dependent olefin epoxidation to all four regioisomeric cis-epoxyeicosatrienoic acids. One of the predominant enzymes responsible for the epoxidation of endogenous cardiac arachidonic acid pools.,online information:CYP2J2 alleles,similarity:Belongs to the cytochrome P450 family.,tissue specificity:Highly expressed in heart, present at lower levels in liver, ileum, jejunum, colon, and kidney.,

• 功能：
• fatty acid metabolic process, icosanoid metabolic process, regulation of heart contraction, unsaturated fatty acid metabolic process, regulation of system process, oxidation reduction,

• 细胞定位：
• Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane ; Peripheral membrane protein.

• 组织表达：
• Highly expressed in heart, present at lower levels in liver, kidney and skeletal muscle (at protein level).

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