Total p52 S6 kinase Cell-Based Colorimetric ELISA Kit

  • 货号:KA3873C
  • 应用:ELISA
  • 种属:Human;Mouse
    • 基因名称:
    • RPS6KC1
    • Human Swiss Prot No:
    • Q96S38
    • Mouse Swiss Prot No:
    • Q8BLK9
    • 储存:
    • 2-8°C/6 months
    • 其他名称:
    • Ribosomal protein S6 kinase delta-1 (S6K-delta-1) (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein)
    • 检测方法:
    • Colorimetric
    • 背景:
    • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,caution:Instead of Lys-820, Arg-820 is found at the binding site.,domain:The first protein kinase domain appears to be a pseudokinase domain as it does not contain the classical characteristics, such as the ATP-binding motif, ATP-binding site and active site.,function:May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. S6 kinase subfamily.,similarity:Contains 1 MIT domain.,similarity:Contains 1 PX (phox homology) domain.,similarity:Contains 2 protein kinase domains.,subcellular location:Also found in some small dot-like or ring-shaped early endosome structures.,subunit:Interacts with SPHK1 and phosphatidylinositol 3-phosphate.,tissue specificity:Highly expressed in testis, skeletal muscle, brain, heart, placenta, kidney and liver and weakly expressed in thymus, small intestine, lung and colon.,
    • 功能:
    • protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, phosphorylation,
    • 细胞定位:
    • Cytoplasm . Membrane . Early endosome .
    • 组织表达:
    • Highly expressed in testis, skeletal muscle, brain, heart, placenta, kidney and liver and weakly expressed in thymus, small intestine, lung and colon.