• 基因名称：
• KSR2

• Human Gene Id：
• 283455

• Human Swiss Prot No：
• Q6VAB6

• Mouse Swiss Prot No：
• Q3UVC0

• 储存：
• 2-8°C/6 months

• 其他名称：
• Kinase suppressor of Ras 2 (hKSR2)

• 检测方法：
• Colorimetric

• 背景：
• domain:The protein kinase domain is predicted to be catalytically inactive.,function:Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.,PTM:Phosphorylated on Ser-474 by MARK3.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.,similarity:Contains 1 phorbol-ester/DAG-type zinc finger.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with MAP2K1, MAP3K8, MAPK, RAS and RAF.,tissue specificity:Mainly expressed in brain and kidney.,

• 功能：
• protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, intracellular signaling cascade, phosphorylation,

• 细胞定位：
• Cytoplasm . Membrane ; Peripheral membrane protein .

• 组织表达：
• Mainly expressed in brain and kidney.

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