Total MAST205 Cell-Based Colorimetric ELISA Kit
- 货号：KA3794C
- 应用：ELISA
- 种属：Human;Mouse
- 其他名称：
- Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1)
- 背景：
- catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,function:Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation.,PTM:Phosphorylated and ubiquitinated. N-terminal ubiquitination leads to degradation of MAST2 by proteasome-mediated proteolysis. N-terminal phosphorylation appears to be a prerequisite for ubiquitination.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 protein kinase domain.,subcellular location:Recruited to the sub-membranous area on interaction with PC-LKC.,tissue specificity:Abundant in the testis.,
- 功能：
- regulation of cytokine production, reproductive developmental process, protein amino acid phosphorylation,phosphorus metabolic process, phosphate metabolic process, gamete generation, spermatogenesis, phosphorylation,sexual reproduction, multicellular organism reproduction, regulation of interleukin-12 production, regulation of cytokine biosynthetic process, regulation of interleukin-12 biosynthetic process, male gamete generation, spermatid differentiation, reproductive process in a multicellular organism, reproductive cellular process,
- 细胞定位：
- Cytoplasm, cytoskeleton . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Recruited to the sub-membranous area on interaction with CDHR2.
- 组织表达：
- Abundant in the testis.
